2010 Rogers Cup – Women's singles

Caroline Wozniacki defeated Vera Zvonareva in the final, 6–3, 6–2 to win the women's singles tennis title at the 2010 Canadian Open.

Elena Dementieva was the defending champion, but lost in the third round to Zheng Jie.

Seeds
The top eight seeds receive a bye into the second round. • # 🇷🇸 Jelena Janković (second round)

• # Caroline Wozniacki (champion)

• # 🇺🇸 Venus Williams (withdrew due to left knee injury)

• # 🇷🇺 Elena Dementieva (third round)

• # 🇧🇪 Kim Clijsters (quarterfinals)

• # 🇮🇹 Francesca Schiavone (quarterfinals)

• # 🇵🇱 Agnieszka Radwańska (third round)

• # 🇷🇺 Vera Zvonareva (final)

• # 🇨🇳 Li Na (third round)

• # 🇧🇾 Victoria Azarenka (semifinals, retired)

• # 🇷🇺 Svetlana Kuznetsova (semifinals)

• # 🇷🇺 Maria Sharapova (withdrew due to left foot injury)

• # 🇧🇪 Yanina Wickmayer (second round)

• # 🇮🇱 Shahar Pe'er (first round)

• # 🇮🇹 Flavia Pennetta (third round)

• # 🇫🇷 Aravane Rezaï (second round)

• # 🇫🇷 Marion Bartoli (quarterfinals)

• # 🇷🇺 Nadia Petrova (second round)