2010 SAP Open – Singles

Radek Štěpánek was the defending champion; however, he lost to Xavier Malisse in the first round. Fernando Verdasco won in the final 3–6, 6–4, 6–4 against Andy Roddick.

Seeds
• # 🇺🇸 Andy Roddick (final)

• # 🇪🇸 Fernando Verdasco (champion)

• # 🇨🇿 Radek Štěpánek (first round)

• # 🇩🇪 Tommy Haas (second round)

• # 🇨🇿 Tomáš Berdych (quarterfinals)

• # 🇩🇪 Philipp Kohlschreiber (quarterfinals)

• # 🇺🇸 Sam Querrey (semifinals)

• # 🇫🇷 Jérémy Chardy (first round)

Seeds
• # 🇺🇸 Kevin Kim (second round)

• # 🇰🇷 Im Kyu-tae (qualifying competition, lucky loser)

• # 🇫🇷 Vincent Millot (qualifying competition)

• # 🇪🇨 Giovanni Lapentti (qualifying competition)

• # 🇺🇸 Ryler DeHeart (qualified)

• # 🇨🇴 Alejandro González (second round)

• # 🇱🇹 Ričardas Berankis (qualified)

• # 🇺🇸 Michael McClune (second round)

Qualifiers
• # 🇺🇸 Tim Smyczek

• # 🇱🇹 Ričardas Berankis

• # 🇷🇺 Alex Bogomolov Jr.

• # 🇺🇸 Ryler DeHeart

Lucky loser
• # 🇰🇷 Im Kyu-tae