2010 Sanremo Tennis Cup – Singles

Kevin Anderson was the defending champion, but chose to compete in Munich instead. Gastón Gaudio won in the final 7–5, 6–0, against Martín Vassallo Argüello.

Seeds
• # 🇷🇺 Teymuraz Gabashvili (semifinals)

• # 🇫🇷 David Guez (first round)

• # 🇪🇸 Albert Ramos-Viñolas (semifinals)

• # 🇦🇷 José Acasuso (second round)

• # 🇩🇪 Tobias Kamke (first round)

• # 🇫🇷 Laurent Recouderc (quarterfinals)

• # 🇦🇷 Diego Junqueira (quarterfinals)

• # 🇩🇪 Dominik Meffert (second round)