2010 Seguros Bolívar Open Medellín – Singles

Juan Ignacio Chela was the defending champion but decided not to participate.

Marcos Daniel won in the final 6–3, 7–5, against Juan Sebastián Cabal.

Seeds
• # 🇦🇷 Horacio Zeballos (quarterfinals)

• # 🇦🇷 Carlos Berlocq (semifinals)

• # 🇦🇷 Brian Dabul (second round)

• # Rui Machado (quarterfinals)

• # 🇧🇷 João Souza (second round)

• # 🇰🇿 Yuri Schukin (first round)

• # Nicolás Massú (first round)

• # 🇪🇸 Daniel Muñoz de la Nava (first round)