2010 Shanghai Rolex Masters – Singles

Andy Murray defeated Roger Federer in the final, 6–3, 6–2 to win the singles tennis title at the 2010 Shanghai Masters.

Nikolay Davydenko was the defending champion, but lost in the second round to Mischa Zverev.

Rafael Nadal's loss in the third round ended his record streak of 21 consecutive Masters 1000 quarterfinals.

Seeds
The top eight seeds receive a bye into the second round. • # 🇪🇸 Rafael Nadal (third round)

• # 🇷🇸 Novak Djokovic (semifinals)

• # Roger Federer (final)

• # 🇬🇧 Andy Murray (champion)

• # 🇸🇪 Robin Söderling (quarterfinals)

• # 🇷🇺 Nikolay Davydenko (second round)

• # 🇨🇿 Tomáš Berdych (third round)

• # 🇷🇺 Mikhail Youzhny (second round)

• # 🇪🇸 Fernando Verdasco (first round)

• # 🇺🇸 Andy Roddick (second round, retired due to a right groin injury)

• # 🇪🇸 David Ferrer (third round)

• # 🇫🇷 Jo-Wilfried Tsonga (quarterfinals)

• # 🇦🇹 Jürgen Melzer (quarterfinals)

• # Marin Čilić (first round)

• # 🇫🇷 Gaël Monfils (second round)

• # 🇪🇸 Nicolás Almagro (first round)

Seeds
• # 🇪🇸 Daniel Gimeno Traver (qualifying competition, lucky loser)

• # 🇫🇷 Jérémy Chardy (qualified)

• # 🇩🇪 Benjamin Becker (qualified)

• # 🇨🇴 Santiago Giraldo (qualifying competition)

• # 🇵🇱 Łukasz Kubot (qualified)

• # Kevin Anderson (qualified)

• # 🇫🇷 Florent Serra (qualified)

• # 🇨🇴 Alejandro Falla (first round)

• # 🇰🇿 Mikhail Kukushkin (qualifying competition)

• # 🇷🇺 Igor Andreev (first round)

• # 🇺🇸 Michael Russell (first round)

• # 🇷🇺 Teymuraz Gabashvili (first round)

• # 🇹🇷 Marsel İlhan (qualified)

• # 🇯🇵 Go Soeda (qualifying competition)

Qualifiers
• # 🇹🇷 Marsel İlhan

• # 🇫🇷 Jérémy Chardy

• # 🇩🇪 Benjamin Becker

• # 🇩🇪 Mischa Zverev

• # 🇵🇱 Łukasz Kubot

• # Kevin Anderson

• # 🇫🇷 Florent Serra

Lucky loser
• # 🇪🇸 Daniel Gimeno Traver