2010 Sicilia Classic – Singles

Adrian Ungur was the defending champion, but was eliminated by Nikola Mektić in the first round.

Attila Balázs won this tournament, by defeating Martin Fischer 7–6(4), 2–6, 6–1 in the final.

Seeds
• # 🇮🇹 Filippo Volandri (second round, retired)

• # 🇮🇹 Simone Bolelli (first round)

• # 🇰🇿 Yuri Schukin (first round)

• # 🇦🇹 Martin Fischer (final)

• # 🇮🇹 Alessio di Mauro (first round)

• # 🇷🇴 Adrian Ungur (first round)

• # 🇫🇷 Éric Prodon (first round)

• # 🇲🇦 Reda El Amrani (first round)