2010 Swedish Open – Women's singles

María José Martínez Sánchez was the defender of title, but withdrew due to a knee injury.

Aravane Rezaï became the new champion, after she won in the final 6–3, 4–6, 6–4, against Gisela Dulko.

Seeds
• # 🇮🇹 Flavia Pennetta (semifinals)

• # 🇫🇷 Aravane Rezaï (champion)

• # 🇨🇿 Lucie Šafářová (semifinals)

• # 🇦🇷 Gisela Dulko (final)

• # 🇪🇸 Arantxa Parra Santonja (quarterfinals)

• # 🇩🇪 Angelique Kerber (first round, Retired)

• # 🇸🇪 Sofia Arvidsson (first round)

• # 🇨🇿 Barbora Záhlavová-Strýcová (quarterfinals)