2010 Toray Pan Pacific Open – Singles

Caroline Wozniacki defeated Elena Dementieva in the final, 1–6, 6–2, 6–3 to win the singles tennis title at the 2010 Pan Pacific Open. It was Dementieva's last WTA Tour singles final before her retirement from the sport later that year.

Maria Sharapova was the defending champion, but lost in the first round to Kimiko Date-Krumm.

Seeds
The top eight seeds receive a bye into the second round. • # Caroline Wozniacki (champion)

• # 🇷🇺 Vera Zvonareva (quarterfinals)

• # 🇷🇸 Jelena Janković (third round)

• # 🇦🇺 Samantha Stosur (second round)

• # 🇮🇹 Francesca Schiavone (semifinals)

• # 🇵🇱 Agnieszka Radwańska (quarterfinals, retired due to left foot pain)

• # 🇷🇺 Elena Dementieva (final)

• # 🇧🇾 Victoria Azarenka (semifinals)

• # 🇨🇳 Li Na (withdrew due to gastrointestinal illness)

• # 🇷🇺 Svetlana Kuznetsova (second round)

• # 🇫🇷 Marion Bartoli (third round, retired due to viral illness)

• # 🇷🇺 Maria Sharapova (first round)

• # 🇮🇱 Shahar Pe'er (second round)

• # 🇫🇷 Aravane Rezaï (second round)

• # 🇷🇺 Nadia Petrova (first round)

• # 🇷🇺 Anastasia Pavlyuchenkova (third round)