2010 UniCredit Czech Open – Singles

Jan Hájek was the defending champion, and he defended his title, because Radek Štěpánek retired in the final.

Seeds
• # 🇨🇿 Radek Štěpánek (final)

• # 🇪🇸 Albert Montañés (second round)

• # 🇷🇴 Victor Hănescu (second round)

• # 🇧🇪 Olivier Rochus (quarterfinals)

• # 🇫🇮 Jarkko Nieminen (quarterfinals)

• # 🇨🇿 Jan Hájek (champion)

• # 🇰🇿 Andrey Golubev (semifinals)

• # 🇺🇸 Michael Russell (first round)