2010 Valencia Open 500 – Singles

Andy Murray was the defending champion, but he was eliminated by Juan Mónaco in the second round.

4th seed David Ferrer defeated Lucky loser Marcel Granollers 7–5, 6–3 in the final match.

Seeds
• # 🇬🇧 Andy Murray (second round)

• # 🇸🇪 Robin Söderling (semifinals)

• # 🇪🇸 Fernando Verdasco (second round)

• # 🇪🇸 David Ferrer (champion)

• # 🇷🇺 Mikhail Youzhny (withdrew because of a back injury)

• # 🇷🇺 Nikolay Davydenko (quarterfinals)

• # 🇫🇷 Jo-Wilfried Tsonga (withdrew)

• # 🇫🇷 Gaël Monfils (quarterfinals)

Seeds
• # 🇪🇸 Marcel Granollers (qualifying competition, lucky loser)

• # Pablo Cuevas (qualified)

• # 🇨🇴 Alejandro Falla (first round)

• # 🇺🇸 Michael Russell (qualified)

• # 🇩🇪 Mischa Zverev (qualifying competition)

• # Frederico Gil (first round)

• # 🇷🇺 Teimuraz Gabashvili (qualified)

• # 🇪🇸 Albert Ramos-Viñolas (qualifying competition, lucky loser)

Qualifiers
• # 🇷🇺 Teimuraz Gabashvili

• # Pablo Cuevas

• # 🇫🇷 Benoît Paire

• # 🇺🇸 Michael Russell

Lucky losers

 * 1) 🇪🇸 Marcel Granollers
 * 2) 🇪🇸 Albert Ramos-Viñolas