2010 Zagreb Open – Singles

Marcos Daniel was the defending champion, but he lost against Yuri Schukin in the semifinals.

Schukin won in the final 6–3, 7–5, against Santiago Ventura.

Seeds
• # 🇧🇷 Marcos Daniel (semifinals)

• # Nicolás Massú (quarterfinals)

• # Blaž Kavčič (quarterfinals)

• # 🇦🇹 Daniel Köllerer (first round, retired)

• # 🇮🇳 Somdev Devvarman (first round)

• # 🇪🇸 Rubén Ramírez Hidalgo (quarterfinals)

• # 🇪🇸 Santiago Ventura (final)

• # Grega Žemlja (second round)