2011 Brisbane International – Men's singles

Andy Roddick was the defending champion, but Robin Söderling defeated him 6–3, 7–5 in the final.

Seeds
• # 🇸🇪 Robin Söderling (champion)

• # 🇺🇸 Andy Roddick (final)

• # 🇪🇸 Fernando Verdasco (first round)

• # 🇺🇸 Mardy Fish (second round)

• # 🇨🇾 Marcos Baghdatis (quarterfinals)

• # 🇪🇸 Feliciano López (second round)

• # 🇩🇪 Florian Mayer (quarterfinals)

• # 🇺🇿 Denis Istomin (second round)