2011 Comerica Bank Challenger – Singles

Marinko Matosevic, the defending champion, didn't participate this year.

Laurynas Grigelis won the title, defeating Ilija Bozoljac 6–2, 7–6(7–4) in the final.

Seeds
• # 🇷🇺 Igor Kunitsyn (semifinals)

• # 🇺🇸 Donald Young (first round)

• # 🇦🇺 Matthew Ebden (quarterfinals)

• # 🇺🇸 Wayne Odesnik (quarterfinals)

• # 🇦🇺 Chris Guccione (first round)

• # 🇦🇺 Carsten Ball (semifinals)

• # 🇷🇸 Ilija Bozoljac (final)

• # 🇧🇦 Amer Delić (first round)