2011 Estoril Open – Women's singles

Anastasija Sevastova was the defending champion, but lost in the first round to Urszula Radwańska.

Anabel Medina Garrigues won in the final against Kristina Barrois, 6–1, 6–2.

Seeds
• # 🇷🇺 Alisa Kleybanova (quarterfinals)

• # 🇦🇺 Jarmila Gajdošová (quarterfinals)

• # 🇨🇿 Klára Zakopalová (quarterfinals)

• # Anastasija Sevastova (first round)

• # 🇺🇸 Bethanie Mattek-Sands (first round)

• # 🇷🇺 Elena Vesnina (second round)

• # 🇨🇳 Zheng Jie (first round)

• # 🇭🇺 Gréta Arn (second round, retired)