2011 Internazionali Femminili di Palermo – Singles

Kaia Kanepi was the defending champion, but decided not to participate.

5th seed Anabel Medina Garrigues defeated 7th seed Polona Hercog in the final, 6–3, 6–2.

Seeds
• # 🇮🇹 Flavia Pennetta (semifinals)

• # 🇮🇹 Roberta Vinci (second round)

• # 🇮🇹 Sara Errani (quarterfinals)

• # 🇨🇿 Klára Zakopalová (quarterfinals)

• # 🇪🇸 Anabel Medina Garrigues (champion)

• # 🇧🇬 Tsvetana Pironkova (quarterfinals)

• # 🇸🇮 Polona Hercog (final)

• # 🇨🇿 Petra Cetkovská (semifinals)