2011 Lexus of Las Vegas Open – Singles

Varvara Lepchenko was the defending champion, but lost in the second round to Kurumi Nara. Romina Oprandi won the title by defeating Alexa Glatch in the final 6–7(2–7), 6–3, 7–6(7–4).

Seeds
• # 🇮🇹 Romina Oprandi (champion)

• # Anna Tatishvili (quarterfinals)

• # 🇺🇸 Varvara Lepchenko (second round)

• # Mirjana Lučić (first round)

• # 🇺🇸 Alison Riske (first round)

• # 🇷🇴 Edina Gallovits-Hall (second round, retired)

• # 🇷🇺 Valeria Savinykh (second round)

• # 🇺🇸 Jamie Hampton (quarterfinals)