2011 Mutua Madrid Open – Women's singles

Petra Kvitová defeated Victoria Azarenka in the final, 7–6(7–3), 6–4 to win the women's singles tennis title at the 2011 Madrid Open. It was her first Premier Mandatory title, and her third title of the year.

Aravane Rezaï was the defending champion, but was defeated by Sofia Arvidsson in the first round.

This tournament marked the final professional appearance of former world No. 1 and Olympic silver medalist Dinara Safina; she lost to Julia Görges in the second round.

Seeds
• # Caroline Wozniacki (third round)

• # 🇷🇺 Vera Zvonareva (third round)

• # 🇮🇹 Francesca Schiavone (third round)

• # 🇧🇾 Victoria Azarenka (final)

• # 🇦🇺 Samantha Stosur (third round)

• # 🇨🇳 Li Na (semifinals)

• # 🇷🇸 Jelena Janković (second round)

• # 🇷🇺 Maria Sharapova (third round)

• # 🇮🇱 Shahar Pe'er (first round)

• # 🇵🇱 Agnieszka Radwańska (second round)

• # 🇫🇷 Marion Bartoli (second round)

• # 🇷🇺 Svetlana Kuznetsova (first round)

• # 🇩🇪 Andrea Petkovic (second round)

• # 🇪🇪 Kaia Kanepi (first round)

• # 🇷🇸 Ana Ivanovic (first round)

• # 🇨🇿 Petra Kvitová (champion)