2011 Sarasota Open – Singles

Kei Nishikori was the defending champion but chose not to participate.

James Blake defeated Alex Bogomolov Jr. in the final (6–2, 6–2) to win the title.

Seeds

 * 1) 🇺🇸 Ryan Sweeting (semifinals)
 * 2) 🇺🇸 Michael Russell (quarterfinals)
 * 3) 🇯🇵 Go Soeda (second round)
 * 4) 🇺🇸 Donald Young (second round)
 * 5) 🇦🇷 Brian Dabul (first round, retired due to fatigue)
 * 6) 🇺🇸 Alex Bogomolov Jr. (final)
 * 7) 🇫🇷 Éric Prodon (quarterfinals, withdrew due to an abdominal strain)
 * 8) 🇺🇸 Ryan Harrison (first round)