2011 Sony Ericsson Open – Men's singles

Novak Djokovic defeated Rafael Nadal in the final, 4–6, 6–3, 7–6(7–4) to win the men's singles tennis title at the 2011 Miami Masters. With the win, Djokovic completed the Sunshine Double, having also won Indian Wells the fortnight before (also defeating Nadal in the final). Djokovic's unbeaten streak to the start of the 2011 season was extended to 24–0, and an overall winning streak of 26 matches.

Andy Roddick was the defending champion, but lost to Pablo Cuevas in the second round.

Seeds
All seeds received a bye into the second round. • # 🇪🇸 Rafael Nadal (final)

• # 🇷🇸 Novak Djokovic (champion)

• # Roger Federer (semifinals)

• # 🇸🇪 Robin Söderling (third round)

• # Andy Murray (second round)

• # 🇪🇸 David Ferrer (quarterfinals)

• # 🇨🇿 Tomáš Berdych (quarterfinals)

• # 🇺🇸 Andy Roddick (second round)

• # 🇪🇸 Fernando Verdasco (second round)

• # 🇦🇹 Jürgen Melzer (second round)

• # 🇪🇸 Nicolás Almagro (third round)

• # Stanislas Wawrinka (second round)

• # 🇷🇺 Mikhail Youzhny (third round)

• # 🇺🇸 Mardy Fish (semifinals)

• # 🇫🇷 Jo-Wilfried Tsonga (third round)

• # 🇷🇸 Viktor Troicki (fourth round)

• # 🇫🇷 Richard Gasquet (third round)

• # Marin Čilić (second round)

• # 🇺🇸 Sam Querrey (third round)

• # 🇪🇸 Albert Montañés (second round, retired due to neck problems)

• # 🇺🇦 Alexandr Dolgopolov (fourth round)

• # 🇨🇾 Marcos Baghdatis (second round)

• # 🇫🇷 Michaël Llodra (third round)

• # 🇪🇸 Guillermo García López (second round)

• # 🇫🇷 Gilles Simon (quarterfinals, retired due to stiff neck)

• # 🇦🇷 Juan Ignacio Chela (second round)

• # 🇧🇷 Thomaz Bellucci (second round)

• # Ernests Gulbis (second round)

• # 🇩🇪 Philipp Kohlschreiber (second round)

• # 🇺🇸 John Isner (fourth round)

• # 🇨🇦 Milos Raonic (second round)

• # 🇦🇷 Juan Mónaco (third round)