2011 Sony Ericsson Open – Women's singles

Victoria Azarenka defeated Maria Sharapova in the final, 6–1, 6–4 to win the women's singles tennis title at the 2011 Miami Open. It was her second Miami Open title.

Kim Clijsters was the defending champion, but lost to Victoria Azarenka in the quarterfinals in a rematch of the previous year's fourth-round match.

Seeds
All seeds received a bye into the second round. • # Caroline Wozniacki (fourth round)

• # 🇧🇪 Kim Clijsters (quarterfinals)

• # 🇷🇺 Vera Zvonareva (semifinals)

• # 🇦🇺 Samantha Stosur (fourth round)

• # 🇮🇹 Francesca Schiavone (fourth round)

• # 🇷🇸 Jelena Janković (quarterfinals)

• # 🇨🇳 Li Na (second round)

• # 🇧🇾 Victoria Azarenka (champion)

• # 🇵🇱 Agnieszka Radwańska (quarterfinals)

• # 🇮🇱 Shahar Pe'er (second round)

• # 🇷🇺 Svetlana Kuznetsova (third round)

• # 🇨🇿 Petra Kvitová (third round)

• # 🇮🇹 Flavia Pennetta (second round)

• # 🇪🇪 Kaia Kanepi (second round)

• # 🇫🇷 Marion Bartoli (fourth round)

• # 🇷🇺 Maria Sharapova (final)

• # 🇷🇺 Anastasia Pavlyuchenkova (fourth round)

• # 🇷🇺 Nadia Petrova (second round, retired due to injury)

• # 🇷🇸 Ana Ivanovic (fourth round)

• # 🇫🇷 Aravane Rezaï (second round)

• # 🇩🇪 Andrea Petkovic (semifinals)

• # 🇷🇺 Alisa Kleybanova (second round)

• # 🇧🇪 Yanina Wickmayer (second round)

• # 🇷🇺 Maria Kirilenko (third round)

• # 🇸🇰 Dominika Cibulková (third round)

• # 🇷🇴 Alexandra Dulgheru (quarterfinals)

• # 🇪🇸 María José Martínez Sánchez (third round)

• # 🇦🇺 Jarmila Groth (third round)

• # 🇸🇰 Daniela Hantuchová (third round)

• # 🇨🇿 Lucie Šafářová (third round)

• # 🇧🇬 Tsvetana Pironkova (second round)

• # 🇨🇿 Klára Zakopalová (third round)