2012–13 SS Lazio season

The 2012–13 season was the 113th season in Società Sportiva Lazio's history and their 25th consecutive season in the top-flight of Italian football.

Pre-season
During the pre-season, Lazio bought Ederson from Lyon, Antonio Candreva from Udinese and Michaël Ciani from Bordeaux.

Play-off round
Note 1: Mura 05 played their home match at Ljudski vrt, Maribor as their own Fazanerija City Stadium did not meet UEFA criteria.

Round of 16
Note 2: The first match that was played behind closed doors due to the punishment handed to Lazio by UEFA following racism issue of their 300 fans at Stadio Olimpico in a match against Borussia Mönchengladbach in second leg of 2012–13 UEFA Europa League round of 32.

Quarter-finals
Note 3: The second match that was played behind closed doors due to the punishment handed to Lazio by UEFA following racism issue of their 300 fans at Stadio Olimpico in a match against Borussia Mönchengladbach in second leg of 2012–13 UEFA Europa League round of 32.

Appearances and goals
! colspan="15" style="background:#dcdcdc; text-align:center"| Goalkeepers

! colspan="15" style="background:#dcdcdc; text-align:center"| Defenders

! colspan="15" style="background:#dcdcdc; text-align:center"| Midfielders

! colspan="15" style="background:#dcdcdc; text-align:center"| Forwards

! colspan="15" style="background:#dcdcdc; text-align:center"| Players transferred out during the season