2012 Aberto Santa Catarina de Tenis – Singles

José Acasuso was the defending champion but decided not to participate. Antonio Veić won the title when his opponent Paul Capdeville retired during the final match. Veić was leading 3–6, 6–4, 5–2.

Seeds
• # 🇸🇮 Blaž Kavčič (semifinals)

• # 🇧🇷 Rogério Dutra da Silva (quarterfinals)

• # Paul Capdeville (final, retired)

• # Antonio Veić (champion)

• # 🇧🇷 Thiago Alves (quarterfinals)

• # 🇦🇺 James Duckworth (quarterfinals)

• # 🇷🇸 Nikola Ćirić (first round)

• # Gastão Elias (quarterfinals)