2012 FINA World Swimming Championships (25 m) – Women's 100 metre individual medley

The women's 100 metre individual medley event at the 11th FINA World Swimming Championships (25m) took place 13 – 14 December 2012 at the Sinan Erdem Dome.

Records
Prior to this competition, the existing world and championship records were as follows.

The following records were established during the competition:

Final
The final was held at 20:52.