2012 FINA World Swimming Championships (25 m) – Women's 4 × 100 metre medley relay

The women's 4x100 metre medley relay event at the 11th FINA World Swimming Championships (25m) took place 14 December 2012 at the Sinan Erdem Dome.

Records
Prior to this competition, the existing world and championship records were as follows.

No new records were set during this competition.

Heats
18 teams participated in 2 heats.

Final
The final was held at 21:16.