2012 Goldwater Women's Tennis Classic – Singles

Sesil Karatantcheva was the defending champion, but lost to Shelby Rogers in the first round.

Madison Keys won the title, defeating Maria Sanchez in the final, 6–3, 7–6(7–1).

Seeds
• # 🇮🇹 Camila Giorgi (quarterfinals)

• # 🇰🇿 Sesil Karatantcheva (first round)

• # 🇺🇸 Melanie Oudin (first round)

• # Michelle Larcher de Brito (quarterfinals)

• # Mirjana Lučić (quarterfinals)

• # 🇺🇸 Alexa Glatch (first round)

• # 🇺🇸 Mallory Burdette (first round)

• # 🇺🇸 Maria Sanchez (final)