2012 Jalisco Open – Singles

Paul Capdeville was the defending champion. Thiago Alves won the title by defeating Paolo Lorenzi 6–3, 7–6(7–4) in the final.

Seeds
• # 🇫🇷 Édouard Roger-Vasselin (second round)

• # 🇩🇪 Matthias Bachinger (first round)

• # 🇮🇹 Paolo Lorenzi (final)

• # 🇨🇦 Vasek Pospisil (second round)

• # Rik de Voest (first round)

• # 🇧🇷 Ricardo Mello (first round)

• # 🇪🇪 Jürgen Zopp (first round)

• # Izak van der Merwe (first round)