2012 Karshi Challenger – Singles

Denis Istomin was the defending champion, but chose not to compete. Igor Kunitsyn won the title, defeating Dzmitry Zhyrmont 7–6(12–10), 6–2 in the final.

Seeds
• # 🇷🇺 Igor Kunitsyn (champion)

• # 🇷🇸 Dušan Lajović (quarterfinals)

• # 🇷🇺 Konstantin Kravchuk (second round)

• # 🇨🇳 Wu Di (semifinals)

• # 🇺🇦 Ivan Sergeyev (semifinals)

• # 🇺🇦 Illya Marchenko (first round)

• # 🇸🇰 Kamil Čapkovič (quarterfinals)

• # 🇦🇺 Brydan Klein (first round)