2012 Knoxville Challenger – Doubles

Steve Johnson and Austin Krajicek were the defending champions but Johnson decided not to participate. Krajicek played alongside Devin Britton. Alex Kuznetsov and Mischa Zverev defeated Jean Andersen and Izak van der Merwe 6–4, 6–2 in the final.

Seeds
• # 🇦🇺 John Peers / 🇦🇺 John-Patrick Smith (first round)

• # 🇷🇺 Alex Bogomolov Jr. / 🇺🇸 Bobby Reynolds (second round, withdrew due to Bogomolov's injury)

• # 🇷🇴 Andrei Dăescu / 🇦🇺 Adam Hubble (first round)

• # 🇺🇸 Devin Britton / 🇺🇸 Austin Krajicek (quarterfinals)