2012 Odlum Brown Vancouver Open – Men's singles

James Ward was the defending champion, but decided not to participate. Igor Sijsling won the title, defeating Sergei Bubka 6–1, 7–5 in the final.

Seeds
• # Igor Sijsling (champion)

• # 🇮🇱 Dudi Sela (semifinals)

• # 🇺🇸 Rajeev Ram (first round)

• # 🇧🇪 Ruben Bemelmans (quarterfinals)

• # 🇨🇦 Frank Dancevic (semifinals)

• # 🇺🇦 Sergei Bubka (final)

• # 🇹🇭 Danai Udomchoke (quarterfinals)

• # Izak van der Merwe (first round)