2012 Sparta Prague Open – Singles

Magdaléna Rybáriková was the defending champion, but she withdrew from the competition.

Lucie Šafářová defeated Klára Zakopalová in the final 6–3, 7–5.

Seeds
• # 🇨🇿 Lucie Šafářová (champion)

• # 🇨🇿 Klára Zakopalová (final)

• # 🇨🇿 Barbora Záhlavová-Strýcová (first round)

• # 🇭🇺 Tímea Babos (second round)

• # Eleni Daniilidou (first round)

• # 🇬🇧 Elena Baltacha (semifinals)

• # 🇯🇵 Kimiko Date-Krumm (quarterfinals)

• # 🇯🇵 Ayumi Morita (quarterfinals)