2012 Tiburon Challenger – Singles

Ivo Karlović was the defending champion but decided not to participate. Jack Sock won the final against Mischa Zverev 6–1, 1–6, 7–6(7–3).

Seeds
• # 🇩🇪 Benjamin Becker (second round, withdrew due to abductor pain)

• # 🇺🇸 James Blake (quarterfinals)

• # 🇺🇸 Ryan Sweeting (first round)

• # 🇺🇸 Wayne Odesnik (first round)

• # 🇮🇹 Matteo Viola (first round)

• # 🇺🇸 Tim Smyczek (first round)

• # 🇺🇸 Denis Kudla (quarterfinals)

• # 🇺🇸 Bobby Reynolds (semifinals)