2012 US Open – Boys' singles

Oliver Golding was the defending champion, but was no longer eligible to compete.

Filip Peliwo won the 2012 title defeating Liam Broady in the final 6–2, 2–6, 7–5, claiming his second consecutive and overall junior grand slam title, having previously won the 2012 Wimbledon Boys' title.

Seeds
• # 🇧🇪 Kimmer Coppejans (quarterfinals)

• # 🇨🇦 Filip Peliwo (champion)

• # 🇮🇹 Gianluigi Quinzi (quarterfinals)

• # 🇧🇷 Thiago Monteiro (second round)

• # 🇺🇸 Mitchell Krueger (first round)

• # 🇷🇸 Nikola Milojević (first round)

• # 🇦🇺 Nick Kyrgios (quarterfinals)

• # 🇯🇵 Kaichi Uchida (semifinals)

• # Frederico Ferreira Silva (third round)

• # 🇮🇹 Stefano Napolitano (first round, retired)

• # 🇩🇪 Daniel Masur (second round)

• # 🇬🇧 Joshua Ward-Hibbert (second round)

• # 🇬🇧 Liam Broady (final)

• # 🇺🇸 Noah Rubin (first round)

• # 🇺🇸 Mackenzie McDonald (first round)

• # 🇧🇪 Julien Cagnina (third round)

Qualifiers
• # 🇫🇷 Maxime Hamou

• # 🇪🇸 José António Salazar Martín

• # 🇺🇸 Michael Mmoh

• # 🇮🇱 Or Ram-Harel

• # Vasco Mensurado

• # 🇮🇳 Sumit Nagal

• # 🇯🇵 Shotaro Goto

• # 🇷🇺 Karen Khachanov