2013 Italian Open – Men's singles

Defending champion Rafael Nadal defeated Roger Federer in the final, 6–1, 6–3 to win the men's singles tennis title at the 2013 Italian Open. It was his record-extending seventh Italian Open title.

Seeds
The top eight seeds receive a bye into the second round : • # 🇷🇸 Novak Djokovic (quarterfinals)

• # Roger Federer (final)

• # 🇬🇧 Andy Murray (second round, retired because of a back injury)

• # 🇪🇸 David Ferrer (quarterfinals)

• # 🇪🇸 Rafael Nadal (champion)

• # 🇨🇿 Tomáš Berdych (semifinals)

• # 🇦🇷 Juan Martín del Potro (third round)

• # 🇫🇷 Jo-Wilfried Tsonga (second round)

• # 🇫🇷 Richard Gasquet (third round)

• # 🇷🇸 Janko Tipsarević (withdrew because of bronchitis)

• # Marin Čilić (second round)

• # 🇪🇸 Nicolás Almagro (first round)

• # 🇩🇪 Tommy Haas (first round)

• # 🇨🇦 Milos Raonic (first round)

• # Stan Wawrinka (second round, withdrew because of a thigh injury)

• # 🇯🇵 Kei Nishikori (second round)

Seeds
• # 🇨🇿 Lukáš Rosol (qualifying competition, lucky loser)

• # Ernests Gulbis (qualified)

• # 🇸🇮 Grega Žemlja (qualifying competition)

• # 🇷🇺 Dmitry Tursunov (first round, retired)

• # 🇦🇷 Carlos Berlocq (qualified)

• # 🇱🇹 Ričardas Berankis (first round)

• # 🇷🇺 Evgeny Donskoy (first round)

• # 🇨🇴 Santiago Giraldo (qualified)

• # 🇷🇺 Andrey Kuznetsov (qualified)

• # 🇧🇷 Rogério Dutra da Silva (first round)

• # Thiemo de Bakker (first round)

• # 🇪🇸 Albert Montañés (qualified)

• # 🇨🇦 Jesse Levine (first round)

• # 🇸🇮 Blaž Kavčič (qualifying competition)

Qualifiers
• # 🇷🇺 Andrey Kuznetsov

• # Ernests Gulbis

• # 🇰🇿 Andrey Golubev

• # 🇨🇿 Jan Hájek

• # 🇦🇷 Carlos Berlocq

• # 🇪🇸 Albert Montañés

• # 🇨🇴 Santiago Giraldo

Lucky losers

 * 1) 🇨🇿 Lukáš Rosol