2013 San Luis Open Challenger – Singles

Rubén Ramírez Hidalgo was the defending champion, but chose not to compete. Alessio di Mauro defeated Daniel Kosakowski 4–6, 6–3, 6–2 in the final to win the title.

Seeds
• # 🇦🇺 John Millman (second round)

• # 🇫🇷 Jonathan Dasnières de Veigy (second round)

• # 🇦🇷 Diego Sebastián Schwartzman (first round)

• # Marco Chiudinelli (semifinals)

• # 🇹🇳 Malek Jaziri (second round)

• # 🇩🇪 Peter Gojowczyk (quarterfinals)

• # 🇸🇰 Andrej Martin (first round)

• # 🇦🇷 Agustín Velotti (quarterfinals, withdrew)