2013 US Open – Wheelchair quad singles

Lucas Sithole defeated the two-time defending champion David Wagner in the final, 3–6, 6–4, 6–4 to win the quad singles wheelchair tennis title at the 2013 US Open.

There was no competition in 2012 due to a schedule conflict with the 2012 Summer Paralympics.

Round robin
''Standings are determined by: 1. number of wins; 2. number of matches; 3. in two-players-ties, head-to-head records; 4. in three-players-ties, percentage of sets won, or of games won; 5. steering-committee decision.''