2013 VTR Open – Singles

Horacio Zeballos defeated Rafael Nadal in the final, 6–7(2–7), 7–6(8–6), 6–4 to win the singles tennis title at the 2013 Chile Open. It was Nadal's first tournament in eight months.

Juan Mónaco was the defending champion, but lost to Guillaume Rufin in the second round.

Seeds
The top four seeds receive a bye into the second round. • # 🇪🇸 Rafael Nadal (final)

• # 🇦🇷 Juan Mónaco (second round)

• # 🇫🇷 Jérémy Chardy (semifinals)

• # 🇪🇸 Pablo Andújar (second round)

• # 🇪🇸 Albert Ramos (quarterfinals)

• # 🇮🇹 Paolo Lorenzi (quarterfinals)

• # 🇪🇸 Daniel Gimeno Traver (quarterfinals)

• # 🇦🇷 Carlos Berlocq (semifinals)

Seeds
• # 🇦🇷 Federico Delbonis (qualified)

• # 🇧🇷 João Souza (first round)

• # Gastão Elias (qualifying competition)

• # Paul Capdeville (first round)

• # 🇩🇪 Dustin Brown (first round)

• # 🇷🇸 Dušan Lajović (qualified)

• # 🇦🇷 Diego Schwartzman (qualified)

• # 🇦🇷 Guido Andreozzi (qualifying competition)

Qualifiers
• # 🇦🇷 Federico Delbonis

• # 🇦🇷 Diego Schwartzman

• # 🇷🇸 Dušan Lajović

• # 🇮🇹 Gianluca Naso