2015–16 Missouri State Lady Bears basketball team

The 2015–16 Missouri State Lady Bears basketball team represented Missouri State University during the 2015–16 NCAA Division I women's basketball season. The Lady Bears, led by third year head coach Kellie Harper, played their home games at JQH Arena and were members of the Missouri Valley Conference. They finished the season 24–10, 14–4 in MVC play to finish in a tie for second place. They won the Missouri Valley women's tournament to earn an automatic trip to the NCAA Women's Basketball where they lost to Texas A&M in the first round.

Schedule
! colspan="9" style="background:maroon; color:#fff;"| Exhibition

! colspan="9" style="background:maroon; color:#fff;"| Non-conference regular season

! colspan="9" style="background:maroon; color:#fff;"| Missouri Valley regular season

! colspan="9" style="background:maroon; color:#fff;"| Missouri Valley Women's Tournament

! colspan="9" style="background:maroon; color:#fff;"| NCAA Women's Tournament