2015 Comerica Bank Challenger – Singles

Marcos Baghdatis was the defending champion but chose not to compete.

John Millman won the tournament, defeating Austin Krajicek in the final, 7–5, 2–6, 6–3.

Seeds

 * 1) 🇦🇺 John Millman (champion)
 * 2) 🇹🇳 Malek Jaziri (quarterfinals)
 * 3) 🇬🇧 Kyle Edmund (semifinals)
 * 4) 🇺🇸 Bjorn Fratangelo (semifinals)
 * 5) 🇯🇵 Taro Daniel (quarterfinals)
 * 6) 🇦🇺 Matthew Ebden (quarterfinals)
 * 7) 🇺🇸 Austin Krajicek (final)
 * 8) 🇯🇵 Yoshihito Nishioka (quarterfinals)