2015 Open de Nice Côte d'Azur – Singles

Ernests Gulbis was the defending champion, but lost to Dominic Thiem in the quarterfinals. Thiem went on to win his first ATP title, defeating Leonardo Mayer in the final, 6–7(8–10), 7–5, 7–6(7–2).

Seeds
The top four seeds receive a bye into the second round. • #🇫🇷 Gilles Simon (withdrew)

• #🇺🇸 John Isner (semifinals)

• # Ernests Gulbis (quarterfinals)

• #🇦🇷 Leonardo Mayer (final)

• #🇦🇺 Bernard Tomic (first round, retired due to a virus)

• #🇦🇺 Nick Kyrgios (second round, retired due to an elbow injury)

• #🇺🇸 Jack Sock (first round)

• #🇦🇷 Juan Mónaco (quarterfinals)

Seeds
• # 🇦🇺 Sam Groth (qualified)

• # 🇧🇪 Ruben Bemelmans (qualified)

• # 🇫🇷 Gianni Mina (qualified)

• # Ante Pavić (qualifying competition)

• # 🇺🇸 Frances Tiafoe (qualifying competition, lucky loser)

• # 🇫🇷 Quentin Halys (qualifying competition, withdrew, lucky loser)

• # 🇫🇷 Fabrice Martin (second round)

• # 🇦🇹 Bastian Trinker (second round)

Qualifiers
• # 🇦🇺 Sam Groth

• # 🇧🇪 Ruben Bemelmans

• # 🇫🇷 Gianni Mina

• # 🇳🇿 Michael Venus

Lucky losers
• # 🇺🇸 Frances Tiafoe

• # 🇫🇷 Quentin Halys