2015 Southern Illinois Salukis football team

The 2015 Southern Illinois Salukis football team represented Southern Illinois University Carbondale as a member of the Missouri Valley Football Conference (MVFC) during the 2015 NCAA Division I FCS football season. Led by Dale Lennon in his eighth and final season as head coach, the Salukis compiled an overall record of 3–8 with a mark of 2–6 in conference play, placing ninth in the MVFC. Southern Illinois played home games at Saluki Stadium in Carbondale, Illinois.

On November 30, head coach Lennon was fired. He finished his tenure at Southern Illinois with an eight-year record of 51–42.