2015 Winston-Salem Open – Singles

Lukáš Rosol was the defending champion, but lost to Jerzy Janowicz in the second round. Kevin Anderson won the title defeating in the final Pierre-Hugues Herbert with the score 6–4, 7–5.

Seeds
All seeds receive a bye into the second round. • 🇫🇷 Gilles Simon (second round)

• Kevin Anderson (champion)

• 🇫🇷 Jo-Wilfried Tsonga (third round)

• 🇷🇸 Viktor Troicki (second round)

• 🇪🇸 Guillermo García López (second round)

• 🇧🇷 Thomaz Bellucci (quarterfinals)

• 🇺🇸 Sam Querrey (second round)

• Borna Ćorić (quarterfinals)

• 🇫🇷 Benoît Paire (second round)

• João Sousa (second round)

• 🇨🇿 Jiří Veselý (third round)

• 🇪🇸 Pablo Andújar (second round)

• 🇺🇸 Steve Johnson (semifinals)

• 🇨🇾 Marcos Baghdatis (second round)

• 🇷🇺 Teymuraz Gabashvili (third round)

• 🇵🇱 Jerzy Janowicz (third round)

Seeds
• # 🇸🇰 Martin Kližan (qualified)

• # 🇫🇷 Lucas Pouille (second round)

• # 🇲🇩 Radu Albot (second round)

• # 🇧🇦 Damir Džumhur (first round)

• # 🇮🇹 Marco Cecchinato (qualified)

• # 🇧🇪 Kimmer Coppejans (first round)

• # 🇺🇸 Bjorn Fratangelo (qualifying competition)

• # 🇺🇸 Ryan Harrison (qualifying competition)

Qualifiers
• # 🇸🇰 Martin Kližan

• # 🇫🇷 Pierre-Hugues Herbert

• # 🇺🇸 Frances Tiafoe

• # 🇮🇹 Marco Cecchinato