2016 İstanbul Cup – Singles

Lesia Tsurenko was the defending champion, but lost in the first round to Sorana Cîrstea.

Çağla Büyükakçay won her first WTA title, defeating Danka Kovinić in the final, 3–6, 6–2, 6–3.

Seeds
• #🇸🇰 Anna Karolína Schmiedlová (first round)

• #🇧🇪 Yanina Wickmayer (first round)

• #🇺🇦 Lesia Tsurenko (first round)

• #🇧🇪 Kirsten Flipkens (second round)

• #🇲🇪 Danka Kovinić (final)

• #🇯🇵 Nao Hibino (quarterfinals)

• #🇺🇦 Kateryna Bondarenko (second round)

• #🇸🇪 Johanna Larsson (second round)

Seeds
• # Maria Sakkari (qualified)

• # 🇺🇦 Kateryna Kozlova (moved to main draw)

• # Romina Oprandi (first round)

• # 🇸🇰 Kristína Kučová (qualified)

• # 🇷🇴 Sorana Cîrstea (qualified)

• # 🇺🇦 Maryna Zanevska (qualified)

• # 🇨🇿 Tereza Martincová (qualifying competition, retired)

• # 🇳🇿 Marina Erakovic (qualifying competition)

• # 🇷🇺 Polina Leykina (first round)

• # 🇨🇳 Lu Jiajing (qualifying competition)

• # 🇫🇷 Myrtille Georges (qualifying competition)

• # 🇪🇸 Laura Pous Tió (first round)

• # 🇷🇺 Marina Melnikova (qualified)

Qualifiers
• # Maria Sakkari

• # 🇷🇺 Marina Melnikova

• # 🇭🇺 Réka-Luca Jani

• # 🇸🇰 Kristína Kučová

• # 🇷🇴 Sorana Cîrstea

• # 🇺🇦 Maryna Zanevska