2016 Abierto Mexicano Telcel – Women's singles

Timea Bacsinszky was the defending champion, but chose to compete in Doha instead.

Sloane Stephens won the title, defeating Dominika Cibulková in the final, 6–4, 4–6, 7–6(7–5).

Seeds
• #🇧🇾 Victoria Azarenka (second round, withdrew because of a left wrist injury)

• #🇺🇸 Sloane Stephens (champion)

• #🇷🇺 Anastasia Pavlyuchenkova (quarterfinals)

• #🇬🇧 Johanna Konta (second round)

• #🇧🇪 Alison Van Uytvanck (first round)

• #🇸🇪 Johanna Larsson (quarterfinals)

• #🇲🇪 Danka Kovinić (second round)

• #🇧🇪 Yanina Wickmayer (semifinals)

Seeds
• # 🇺🇸 Lauren Davis (qualifying competition)

• # Kiki Bertens (qualified)

• # 🇵🇱 Urszula Radwańska (qualified)

• # 🇺🇸 Samantha Crawford (qualified)

• # 🇫🇷 Pauline Parmentier (qualifying competition)

• # 🇨🇳 Han Xinyun (qualifying competition)

• # 🇺🇸 Louisa Chirico (qualified)

• # 🇮🇱 Julia Glushko (qualified)

• # 🇪🇸 María Teresa Torró Flor (qualifying competition)

• # Maria Sakkari (qualified)

• # 🇸🇪 Rebecca Peterson (first round)

• # Viktorija Golubic (qualifying competition)

Qualifiers
• # 🇮🇱 Julia Glushko

• # Kiki Bertens

• # 🇵🇱 Urszula Radwańska

• # 🇺🇸 Samantha Crawford

• # 🇺🇸 Louisa Chirico

• # Maria Sakkari