2016 BNP Paribas Masters – Singles

Andy Murray defeated John Isner in the final, 6–3, 6–7(4–7), 6–4 to win the singles tennis title at the 2016 Paris Masters. By reaching the final, Murray secured the world No. 1 ranking for the first time in his career.

Novak Djokovic was the three-time defending champion, but lost to Marin Čilić in the quarterfinals.

As a result of Roger Federer's withdrawal from the tournament, he fell outside of the top 10 in the ATP rankings for the first time since 13 May 2002.

Seeds
All seeds receive a bye into the second round. • 🇷🇸 Novak Djokovic (quarterfinals)

• 🇬🇧 Andy Murray (champion)

• Stan Wawrinka (second round)

• 🇨🇦 Milos Raonic (semifinals, withdrew with a torn right quadricep)

• 🇯🇵 Kei Nishikori (third round)

• 🇦🇹 Dominic Thiem (second round)

• 🇨🇿 Tomáš Berdych (quarterfinals)

• 🇧🇪 David Goffin (third round)

• Marin Čilić (semifinals)

• 🇪🇸 Roberto Bautista Agut (second round)

• 🇫🇷 Jo-Wilfried Tsonga (quarterfinals)

• 🇫🇷 Richard Gasquet (third round)

• 🇫🇷 Lucas Pouille (third round)

• 🇧🇬 Grigor Dimitrov (third round)

• 🇪🇸 David Ferrer (second round)

• Pablo Cuevas (third round)

Seeds
• # 🇷🇺 Mikhail Youzhny (first round)

• # 🇬🇧 Daniel Evans (withdrew)

• # 🇹🇳 Malek Jaziri (qualifying competition)

• # 🇷🇺 Karen Khachanov (withdrew)

• # Robin Haase (qualified)

• # 🇩🇪 Dustin Brown (qualifying competition)

• # 🇺🇸 Taylor Fritz (first round)

• # 🇷🇸 Dušan Lajović (qualified)

• # 🇪🇸 Íñigo Cervantes (first round)

• # 🇨🇿 Adam Pavlásek (first round)

• # 🇮🇹 Andreas Seppi (qualified)

• # 🇯🇵 Yūichi Sugita (first round)

Qualifiers
• # 🇫🇷 Pierre-Hugues Herbert

• # 🇮🇹 Andreas Seppi

• # 🇷🇸 Dušan Lajović

• # 🇩🇪 Jan-Lennard Struff

• # Robin Haase

• # 🇫🇷 Julien Benneteau