2016 Cary Challenger – Singles

Dennis Novikov was the defending champion but lost in the semifinals to James McGee.

McGee won the title after defeating Ernesto Escobedo 1–6, 6–1, 6–4 in the final.

Seeds
• # 🇺🇸 Dennis Novikov (semifinals)

• # 🇺🇸 Frances Tiafoe (semifinals)

• # 🇺🇸 Austin Krajicek (first round)

• # 🇺🇸 Stefan Kozlov (quarterfinals)

• # 🇨🇦 Peter Polansky (quarterfinals)

• # Darian King (second round)

• # Marcelo Arévalo (first round)

• # 🇺🇸 Ernesto Escobedo (final)