2016 Claro Open Barranquilla – Singles

Borna Ćorić was the defending champion but chose not to participate.

Diego Schwartzman won the title after defeating Rogério Dutra Silva 6–4, 6–1 in the final.

Seeds
• # 🇦🇷 Diego Schwartzman (champion)

• # 🇩🇴 Víctor Estrella Burgos (quarterfinals)

• # 🇧🇷 Rogério Dutra Silva (final)

• # 🇨🇴 Santiago Giraldo (semifinals)

• # 🇦🇷 Máximo González (semifinals)

• # 🇨🇴 Alejandro González (quarterfinals)

• # Darian King (first round)

• # Marcelo Arévalo (second round)