2016 Claro Open Bucaramanga – Singles

Daniel Gimeno Traver is the defending champion, but chose not to defend his title. Gerald Melzer won the title defeating Paolo Lorenzi in the final 6–3, 6–1.

Seeds
• # 🇩🇴 Víctor Estrella Burgos (quarterfinals)

• # 🇮🇹 Paolo Lorenzi (final)

• # 🇦🇷 Facundo Bagnis (first round)

• # 🇪🇸 Albert Montañés (first round)

• # 🇧🇷 Rogério Dutra Silva (first round)

• # 🇨🇴 Alejandro Falla (first round)

• # 🇦🇷 Horacio Zeballos (semifinals)

• # Gastão Elias (quarterfinals)