2016 Columbus Challenger 2 – Singles

Mikael Torpegaard was the defending champion but lost in the first round to Taylor Fritz.

Stefan Kozlov won the title after defeating Tennys Sandgren 6–1, 2–6, 6–2 in the final.

Seeds
• # 🇺🇸 Taylor Fritz (quarterfinals)

• # 🇺🇸 Rajeev Ram (withdrew)

• # Henri Laaksonen (semifinals)

• # 🇺🇸 Stefan Kozlov (champion)

• # 🇺🇸 Mitchell Krueger (second round)

• # 🇺🇸 Tennys Sandgren (final)

• # 🇺🇸 Austin Krajicek (first round)

• # 🇮🇪 Sam Barry (semifinals)