2016 Copa Luis Villarejo

The 2016 Copa Luis Villarejo was the first edition of the Copa Luis Villarejo, a cup tournament for clubs in Puerto Rico organized by the Puerto Rican Football Federation. The champions and runners-up of this tournament are eligible to enter the 2017 Caribbean Club Championship, which serves as a qualifying tournament for the 2017 CONCACAF League and 2018 CONCACAF Champions League.

Teams
A total of eight teams participated in this tournament.
 * Bayamón - LNF & PRSL
 * Caguas Sporting - PRSL
 * Criollos de Caguas - LNF
 * Don Bosco - PRSL
 * Guayama - LNF
 * Metropolitan - PRSL
 * Mayagüez - PRSL
 * Puerto Rico FC - NASL

Second legs
Criollos de Caguas FC won 14–2 on aggregate.

Metropolitan FC won 5–3 on aggregate.

Bayamón FC won 8–0 on aggregate.

Puerto Rico FC won 6–0 on aggregate.

Second legs
Criollos de Caguas FC won 5–4 on aggregate.

Puerto Rico FC won 4–0 on aggregate.