2016 FINA World Swimming Championships (25 m) – Women's 400 metre individual medley

The Women's 400 metre individual medley competition of the 2016 FINA World Swimming Championships (25 m) was held on 7 December 2016.

Records
Prior to the competition, the existing world and championship records were as follows.

Heats
The heats were held at 11:49.

Final
The final was held at 19:18.